Linkage Analysis with Dense SNP Maps in Isolated Populations
نویسندگان
چکیده
منابع مشابه
Linkage analysis with dense SNP maps in isolated populations.
OBJECTIVE SNP maps are becoming the gold standard for genetic markers, even for linkage analyses. However, because of the density of SNPs on most high throughput platforms, the resulting significant linkage disequilibrium (LD) can bias classical nonparametric multipoint linkage analyses. This problem may be even stronger in population isolates where LD can extend over larger distances and with ...
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ژورنال
عنوان ژورنال: Human Heredity
سال: 2009
ISSN: 1423-0062,0001-5652
DOI: 10.1159/000212501